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KMID : 0361520130240040186
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Korean Journal of Psychopharmacology
2013 Volume.24 No. 4 p.186 ~ p.189
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Metformin for Treatment of Antipsychotic-Induced Amenorrhea in Female Schizophrenic Patients: Report of Two Cases
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Woo Young-Sup
Bahk Won-Myong
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Abstract
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Amenorrhea is a common adverse event in female patients treated with antipsychotics. Because amenorrhea can produce difficulties for women suffering from schizophrenia, attempts should be made to alleviate antipsychotic-induced amenorrhea. We report two cases of female schizophrenic patients whose antipsychotic-induced amenorrhea were treated with metformin. Two patients who treated with metformin resumed their menstruation within three months. There was no adverse event reported during metformin treatment. This paper presents the rationale for the use of metformin for female patients who suffered from antipsychotic-induced amenorrhea through a literature review.
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KEYWORD
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Schizophrenia, Antipsychotic-induced amenorrhea, Metformin
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